Q. No.ELISA is based on the principle of:
| 1. | Antigen-antibody interaction |
| 2. | Radioactive immunoassay |
| 3. | DNA amplification |
| 4. | Expressed sequence tag |
Subtopic: Molecular Diagnosis |
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Level 1: 80%+
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Which of the following is best for the effective treatment of a disease?
| 1. | Early diagnosis only |
| 2. | Understanding the pathophysiology only |
| 3. | Diagnosing only after the symptoms have manifested |
| 4. | Early diagnosis and understanding its pathophysiology |
Subtopic: Molecular Diagnosis |
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Level 1: 80%+
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How does Polymerase Chain Reaction (PCR) aid in the early diagnosis of diseases?
| 1. | It amplifies the DNA or RNA of the pathogens, making it possible to detect even very low concentrations of a pathogen before symptoms appear. |
| 2. | It neutralizes the pathogens in the bloodstream, reducing the need for further diagnostic tests. |
| 3. | It enhances the immune response of the body, making the pathogens easier to identify. |
| 4. | It directly destroys the pathogen, making early diagnosis unnecessary. |
Subtopic: Molecular Diagnosis |
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Level 1: 80%+
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DNA or RNA segment tagged with a radioactive molecule is called
1. vector
2. probe
3. clone
4. plasmid
Subtopic: Molecular Diagnosis |
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Level 1: 80%+
NEET - 2010
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| Assertion(A): | Polymerase chain reaction serve the purpose of early diagnosis of diseases. |
| Reason(R): | PCR can detect very low concentration of a bacteria or virus, at a time when the symptoms of a disease are not yet visible, by amplification of their nucleic acid. |
| 1. | Both (A) and (R) are true and (R) is the correct explanation of (A) |
| 2. | Both (A) and (R) are true and (R) is not the correct explanation of (A) |
| 3. | (A) is true but (R) is false. |
| 4. | Both (A) and (R) are false. |
Subtopic: Molecular Diagnosis |
93%
Level 1: 80%+
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The ELISA (Enzyme-Linked Immunosorbent Assay) test is widely used for detecting infections. What is the fundamental principle behind ELISA?
| 1. | It directly isolates pathogens from the blood, ensuring rapid diagnosis. |
| 2. | It stimulates immune cells to attack pathogens, providing immediate immunity. |
| 3. | It detects the presence of specific antigens or antibodies through antigen-antibody interactions. |
| 4. | It sequences the DNA of pathogens, identifying infections at the genetic level. |
Subtopic: Molecular Diagnosis |
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Level 1: 80%+
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Polymerase Chain Reaction (PCR) is a powerful technique that can detect extremely low concentrations of bacterial or viral DNA, even before disease symptoms appear. How does PCR achieve this?
| 1. | By directly visualizing pathogens under a high-resolution microscope |
| 2. | By detecting antibodies produced against the pathogen in the patient’s blood |
| 3. | By amplifying the nucleic acid of the pathogen using specific primers and DNA polymerase |
| 4. | By stimulating the immune system to produce a response against the pathogen |
Subtopic: Molecular Diagnosis |
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Level 1: 80%+
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| Assertion(A): | ADA-deficiency causes immunodeficiency. |
| Reason(R): | ADA is crucial for immune system to function. |
| 1. | Both (A) and (R) are True and (R) is the correct explanation of (A). |
| 2. | Both (A) and (R) are True but (R) is not the correct explanation of (A). |
| 3. | (A) is True but (R) is False. |
| 4. | Both (A) and (R) are False. |
Subtopic: Molecular Diagnosis |
89%
Level 1: 80%+
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Which of the following is best for effective treatment of disease?
| 1. | Early diagnosis only |
| 2. | Understanding the pathophysiology only |
| 3. | Diagnosing only after the symptoms have manifested |
| 4. | Early diagnosis and understanding its pathophysiology |
Subtopic: Molecular Diagnosis |
86%
Level 1: 80%+
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Consider the given two statements:
| Assertion (A): | Clone of cells having the mutated gene doesn't appear on photographic film in autoradiography. |
| Reason (R): | The used probes do not have complementarity with the mutated gene. |
| 1. | Both (A) and (R) are True and (R) is the correct explanation of (A). |
| 2. | Both (A) and (R) are True but (R) is not the correct explanation of (A). |
| 3. | (A) is True but (R) is False. |
| 4. | (A) is False but (R) is True. |
Subtopic: Molecular Diagnosis |
86%
Level 1: 80%+
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