How sickle cell anaemia is different from Thalassemia?

(1) Being autosomal recessive

(2) Being a blood disease

(3) Being a qualitative disorder

(4) Involvement of mutation

The genes which are involved in alpha Thalassemia are---- and ----- while in beta thalassemia are----.

(1) HBA1, HBB, HBA2

(2) HBB1 HBB2 HBA

(3) HBB1 HBA HBB2

(4) HBA1 HBA2 HBB

The basis of Thalassemia classification can be-

(1) Which parent is affected

(2) Which chain of haemoglobin molecule is affected

(3) How much a chain is affected

(4) Which gender is showing the disease

Read the following statements with respect to Thalassemia and find the wrong one.

1. Quantitative disorder
2. Different forms of Thalassemia are observed
3. Anaemia is not a characteristic feature of this disease
4. Defect due to mutation and deletion

Find the correct match-

1. Alpha Thalassemia- 11^th chromosome
2. Beta chromosome- 16^th chromosome’
3. Alpha Thalassemia- linked genes
4. Thalassemia- Qualitative trait

Alpha Thalassemia is controlled by ------- on chromosome number----

(1) Linked gene, 11

(2) Linked gene, 16

(3) Unlinked gene, 11

(4) Unlinked gene, 16

Which of the following are correct with respect to Thalassemia?

1. An autosomal dominant disorder
2. Defect due to mutation or deletion
3. Parents will be homozygous for thalassemia
4. Occurs due to vitamin deficiency

Which of the following statements is wrong with respect to beta Thalassemia?

1. Controlled by a single gene.
2. Gene involved is HBA1
3. Gene involved is present on chromosome number 11
4. Occurs due to mutation

If Ram has a brother Shyam suffering from Cystic Fibrosis, what is the probability of Ram being a carrier as his parents are normal?

a.1/4

b. ½

c.2/3

d.3/4